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Proper closure of the CCU lid is critical to your process and instrument function. The lid must be guided down and back at an angle to ensure correct closure, you must confirm no tubing is kinked within the CCU, no tubing is pinched, and never use the CCU as leverage when attaching reagent, spiking buffer, or operating ancillary equipment. Following this advice will help protect tubing integrity, maintain CCU functionality, and support reliable system operation.