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Neuroscience research into psychedelics like psilocybin has shown that these substances dramatically alter brain activity. Contrary to what one might expect, they don't simply increase brain activity. Instead, they decrease the activity of the brain's 'Default Mode Network'—a hub of brain regions associated with our sense of self, our ego, and our autobiographical story. By quieting this network, the brain enters a state of higher entropy, with different regions communicating in new and unusual

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