Number one, El Mencho. His full name is Nemesio Oseguera Cervantes, leader of the Jalisco New Generation Cartel, also known as CJNG. He was one of the most wanted drug bosses in Mexico. El Mencho was known for his strategic smuggling networks, ruthless enforcement tactics, and ability to evade capture for years. His cartel operated across Mexico and into the United States, trafficking cocaine, methamphetamine, and other illicit drugs. In February 2026, Mexican federal forces located his hideout.